A Study of Predictive Factors Affecting Outcome of Intrauterine Tuboperitoneal Insemination

نویسندگان

  • Verma Asha
  • Disha Gupta
چکیده

Infertility management has become more substantial and relevant with an increase in the number of infertile patients as well as advances in the science of reproduction. The objective of our study was to assess the factors predicting the treatment outcome of a new assisted reproductive technique, intrauterine tuboperitoneal insemination (IUTPI) in the treatment of infertile patients. 118 cases, after applying both inclusion and exclusion criteria were enrolled in the study. Patients were given clomiphene citrate for ovarian stimulation followed by injection human chorionic gonadotropin for triggering ovulation. Insemination was then performed with washed husband’s sperm after about 36-40 hours, using 10ml of inseminate. The patient was then called after 2 weeks for urine pregnancy test which, if positive was considered as clinical pregnancy. Out of 118 cases, 27 cases were positive. The pregnancy rate was 22.88%. Endometrial thickness, preovulatory follicle number, prewash sperm motility and post wash sperm motility significantly affected the pregnancy outcome. Factors like patient’s age, BMI<25, bilateral patent tubes and decreased duration of infertility also positively affected the outcome. IUTPI may, thus, become an attractive first line option for infertile couples, considering cost benefits over in vitro fertilization and significantly better pregnancy rate over intrauterine insemination. A knowledge of predictive factors may be of help to offer and counsel patients regarding success of treatment outcome in IUTPI.

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تاریخ انتشار 2017